In the July Biotechniques Jeff Lichtman said most biologists “hope to fail”. He said ” because they like their hypothesis; being unable to disprove it gives them confidence that they’re on the right track”.
He prefers asking questions and looking at big data sets, i.e what happens in animals. My kind of guy. He went on to paraphrase Viktor Hamburger who said “of all his teachers, the only one who was always right was the chick embryo”. I wonder what Viktor would think about HCA?
This week I went to a HTS meeting in DC. Most of the participants were refugees from pharma research groups that have cratered as the drug industry has begun outsourcing research to academics. Don’t the MBAs who now run big pharma know that you get what you pay for? The goal of the meeting was to continue to build a manual for HTS (http://assay.nih.gov). The manual is an incredible resource for people trying to develop assays for screening, regardless of the scale of the project. Check it out.